Semler Scientific Aims for 105,000 BTC by 2027 in Aggressive Accumulation Plan

• Semler Scientific’s shift toward the “Bitcoin Standard” reflects a strategic approach rather than speculation, positioning Bitcoin as a key balance sheet asset.
• The plan is supported by equity issues, debt, and operating cash flow, including a $136 million raise from a recent stock offering.

Semler Scientific, a Nasdaq-listed healthcare technology company, has announced a daring three-year plan to substantially increase its Bitcoin holdings. It aims to own up to 105,000 BTC by the year 2027. Once done, the purchase would make the company among the top five Bitcoin holders, along with Michael Saylor’s Strategy and Metaplanet. 

Inside Semler Scientific’s Aggressive Bitcoin Buying Plan

On Thursday, the plan was published, which proposes an upbeat strategy for increasing the company’s treasury by acquiring Bitcoin. Within the next year, Semler Scientific aims to reach 10,000 BTC, scaling up to 42,000 BTC by the close of 2026, which is almost 10 times its current holdings of 4,449 BTC.

After making Bitcoin its principal treasury asset back in May 2024, Semler has continued to insist that it is not about the speculation; it is more of a strategy. To the leaders of the company, Bitcoin has become part of the core balance sheet instead of being considered an opportunistic investment. The company characterizes this as a shift toward the so-called “Bitcoin Standard” in line with Strategy and its Executive Chairman, Michael Saylor’s initiative.

The acquisition plan will be funded through a combination of equity issues, debt, and the operating cash flow generated. Semler has already shown momentum in this direction, raising over $136 million via a $500 million at-the-market stock offering program it launched in April 2025. Its holdings of Bitcoin had risen to just under $472 million by June, with its incremental purchases including a $17 million BTC buy early this year.

Further, Semler Scientific just hired Joe Burnett as Director of Bitcoin Strategy to lead its developing BTC-centered focus. Burnett, who was formerly with Unchained, has been pushing the idea of corporations to keep Bitcoin in reserve assets. This appointment shows the importance of the company taking a long look at its crypto perspective.

Analyst Take On Semler’s BTC-Focused Move

Market analysts believe that this kind of concentration by a non-crypto-native firm may have far-ranging consequences. Michael Cameron, the co-founder of Superp, observed that Semler’s plan “create demand shocks that ripple into perpetual markets, especially during aggressive accumulation phases,” according to a Decrypt report.

In June 2025, the enterprise value of Semler Scientific is nearly equal to the size of its Bitcoin holding. The company website data has its mNAV (multiple-to-net asset value) at 1.07, implying that the company valuations are becoming more and more linked to its exposure to crypto.

This deepening correlation highlights an overall shift in market perception around Bitcoin’s role in corporate finance. Vincent Liu, Chief Investment Officer of Kronos Research, described the strategy of Semler as one of the trends among businesses that see Bitcoin as a kind of “digital gold.”

He added that macroeconomic instability, particularly in geopolitically tense regions, continues to drive interest in Bitcoin as a hedge against uncertainty. Semler Scientific’s approach aligns with a wave of institutional interest, where some governments are even evaluating Bitcoin as part of national reserves or recognizing it as legal tender.